Mentatcurated
▸ Concept

Genomics

The reading, mapping, and manipulation of entire genetic sequences — the foundation for gene therapies, inherited-disease diagnostics, and drug-target discovery.

In a nutshell

A genome is an organism's complete set of DNA instructions — roughly three billion base pairs in humans. Genomics reads that sequence, compares it across individuals and species, and maps how variation drives disease. That sequence data is now cheap to generate: the cost of sequencing a human genome fell from $100 million in 2001 to under $200 today. The hard part is interpretation — most variants have unknown effects, and the gap between "we can read this" and "we know what it means" is where nearly all the clinical risk lives.

Where it came from

Year2001
SourceHuman Genome Project — first draft published in Nature and Science, February 2001
Why it matteredThe sequencing field predates the project, but the complete-genome frame dates from this publication.

How this connects

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